Endocrine Abstracts

Introduction: The 1-mg overnight low-dose dexamethasone suppression test is used as a screening tool when Cushing’s syndrome is suspected. However, the biological confirmation of this syndrome is based upon the measurement of 24-hour urinary free cortisol and low-dose dexamethasone suppression test (Liddle test). The aim of this study was to assess the performance of the 1-mg overnight low-dose dexamethasone suppression test in the diagnosis of Cushing’s syndrome.</p...

Introduction: Spontaneous hypoglycemia in non-diabetic patients is a rare metabolic emergency caused by multiple etiologies. Factitious hypoglycemia, a form of the Munchausen syndrome, is defined as the surreptitious use of insulin or oral hypoglycemic agents to deliberately induce self-harm. It is one of the most challenging diagnoses associated with significant morbidity and mortality. The aim of this study was to assess the prevalence and the associated factors of factitiou...

Introduction: Poorly controlled hypothyroidism is a chronic disease frequently associated with an impaired quality of life (QoL). However, persistent symptoms may be observed in well-controlled hypothyroid patients, impacting their QoL. The aim of our study was to assess the QoL in patients with well-controlled primary hypothyroidism and to evaluate the relationship between the TSH level and the QoL.Methods: A cross-sectional study was conducted in the o...

IntroductionThyroid hemiagenesis is defined as the absence of one lobe of the thyroid gland. It represents a rare congenital abnormality with a prevalence of 0.05 to 0.2%. The left lobe is more commonly affected than the right lobe. Thyroid hemiagenesis is incidentally found during a routine thyroid screen. Herein, we report a thyroid hemiagenesis revealed by a compensatory hypertrophy of the contralateral thyroid lobe in an adolescent girl with euthyroi...

IntroductionGraves’ disease is typically characterized by the presence of circulating autoantibodies that stimulate the TSH receptor, inducing hyperthyroidism and goiter. Hashimoto’s thyroiditis is an autoimmune disease leading to thyroid tissue destruction by cell and antibody-mediated immune processes. The development of Hashimoto’s thyroiditis following Graves’ disease is rarely reported. Its pathogenesis is not confirmed. Herein, ...

Introduction: The 1-mg overnight low-dose dexamethasone suppression test (DST) has been used to screen for mild autonomous cortisol secretion and Cushing’s syndrome (CS). The aim of the present study was to determine the DST discriminatory threshold confirming the diagnosis of CS.Methods: This was a monocentric retrospective study including patients who were admitted to the Department of Endocrinology of La Rabta Hospital, Tunis between 2014 and 202...

Introduction: Sheehan’s syndrome is a rare cause of hypopituitarism. It is defined by an ischemic necrosis of the pituitary gland following postpartum hemorrhage. Sheehan syndrome is characterized by various endocrine deficiencies. The aim of the present study was to determine the clinical and paraclinical characteristics of women with Sheehan syndrome.Methods: This was a monocentric cross-sectional study including 50 women followed for Sheehan&#146...

Introduction: Hypothyroidism is a prevalent endocrine disease among the elderly. The thyroid hormones have a wide range of effects on the body, and hypothyroidism can significantly impact both physical and mental functions. The objectives of this study were to evaluate the quality of life in patients over 65 years old with substituted hypothyroidism and to assess their relationship with Thyroid Stimulating Hormone (TSH) level.Methods: The study was a cro...

Introduction: Polycystic ovary syndrome is the most common cause of anovulatory infertility in women. Anti-Mullerian Hormone (AMH) was considered a reliable marker for the diagnosis of polycystic ovary syndrome (PCOS). However, AMH level is influenced by age and body mass index. The aim of this study was to analyze the performance of the (LH x AMH)/FSH ratio in the diagnosis of PCOS in women with morbid obesity.Methods: This was a cross-sectional study i...